SELF-ADMINISTRATION OF BIOLOGIC THERAPY IN SEVERE ASTHMA AND CHRONIC RHINOSINUSITIS WITH NASAL POLYPS: COMPLIANCE AND QUALITY OF LIFE IMPROVEMENT

TYPE: Late Breaking Abstract TOPIC: Practice Management and Administration PURPOSE: to analyze compliance clinical response in a group of patients with severe asthma (SA) chronic rhinosinusitis nasal polyps (CRwNP) performing self-administration biologic therapy at home. METHODS: we enrolled (step 5 GINA Guidelines) CRwNP receiving the ambulatory care Pneumology department (ASL 5, La Spezia. They switch At first injection clinic, were educated self-administration. could communicate dedicated nurse any adverse event or question. Asthma Control Test (ACT), Severe Questionnaire (SAQ), Sino-Nasal Outcome (SNOT-22) performed baseline after three months. RESULTS: 10 treated biologics (4 mepolizumab, 3 dupilumab, 2 omalizumab, 1 benralizumab) had All it during scheduled date. mean ACT score was 8.8, SAQ 177.9, SNOT-22 34. months 23.7, 340.3, 6. CONCLUSIONS: home is safe, good an improvement symptoms. CLINICAL IMPLICATIONS: well tolerated, SA Our study suggests importance pathways management diseases shift burden outpatient setting. DISCLOSURE: No significant relationships. KEYWORD: SEVERE ASTHMA, SELF ADMINISTRATION, QUALITY OF LIFE